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KMID : 1149220140220010033
Korean Journal of Oriental Medical Prescription
2014 Volume.22 No. 1 p.33 ~ p.45
Combination Tendency Analysis on Herbal Formula to Treat Insomnia Focused on Zizyphi spinosi Semen
Lee Won-Yung

Jeong Gi-Hoon
Abstract
Objectives : Zizyphi spinosi Semen is widely used for treating insomnia in korea and other oriental country. This study is analyzing combination tendency of Zizyphi spinosi Semen in herbal formula for treating insomnia.

Methods : Herbal formulas for treating insomia were searched in¡ºThe Prescription Dictionary of Traditional Chinese Medicine¡», and checked in each literary source. Then, the herbal formula was divided in two groups : FCZ(The formula group containing Zizyphi spinosi Semen) and FWZ(The formula group without Zizyphi spinosi Semen). FCZ and FWZ were compared by following criteria; ¥¡) Prevalence of herbal formula by period ¥¢) Prevalence of medicinal material's effects ¥£) Prevalence of medicinal material ¥¤) Prevalence of the nature of midicinals ¥¥) Prevalence of flavor of medicinals ¥¦) Prevalence of meridian entry.

Results : 116 Herbal formula met our criteria, and herbal formulas were divided in two groups : FCZ(n=59), FWZ(n=57). The result of prevalence in FCZ is following; Herbal formula prevalence increased as time passed to the Qing(ôè) dynasty. Tonifying and replenishing medicinal(ÜÍìÌå·), tranquillizing medicinal (äÌãêå·), and inducing diuresis to drain dampness medicinal(××â©?ã¥å·) are the three most prevalent types of materia medica. In specifically, Panax ginseng radix(ìÑ߸), Liriopis Tuber(ØêÚ¦ÔÏ), Angelicae Gigantis Radix(Ó×Ïý), Poria Cocos(ÜÚãê), Glycyrrhizae Radix(Êöõ®), Poria cocos(ÜÚ?), Polygalae Radix(êÀò¤), Thuja Orientalis L.(ÛÚí­ìÒ), Paeonia Japonica(ÛÜíËå·), and HgS(?Þã) are combined frequently. The most prevalent nature of medicinals were 'warm ¡¤ microwarm(计¤Ú°è®)' and flavor of medicinals was normal(øÁ). Meridian entrys that frequently combined were heart(ãý), spleen(Þ¡), and liver(ÊÜ).

Conclusion : We found combination tendency of Zizyphi Semen in herbal formula for treating insomnia.
KEYWORD
Zizyphi spinosi Semen, insomnia, herbal formula, combination tendency
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